Aminotetrazole derivatives useful as nitric oxide synthase inhibitors

Derives d'aminotetrazole utiles en tant qu'inhibiteurs de la monoxyde d'azote synthetase

Abstract

Compounds having formula (I) and pharmaceutically acceptable salts thereof, wherein B is NR5R11, wherein R5 is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkynyl and aryl, and R11 is selected from a 3 to 8 member heterocyclyl radical in which at least one member of the ring is carbon and in which 1 to about 4 members are heteroatoms independently selected from oxygen, nitrogen and sulfur and said heterocyclyl radical may be optionally substituted, useful as nitric oxide synthase inhibitors.

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